WormGazer™
Novel biophotonics platform for scalable C. elegans healthspan data
At Magnitude Biosciences, we offer cutting-edge healthspan and lifespan assays powered by our proprietary WormGazer™ technology. These assays provide comprehensive insights into ageing, healthspan, and disease progression using the C. elegans model organism.
Healthspan vs. Lifespan
Scalable, automated, multi-end point health metrics
Our patented biophotonics platform analyses and captures multiple end-point data from living worms, providing rich integrated measures on the effect of your compound or product. In contrast to manual assays, that are well-established in academic research to measure health, ageing, toxicity (death) and disease in C. elegans, our WormGazer™ Technology confers several advantages:

Robust and fast assay workflow with high data reproducibility and sensitivity
Over 80+ years of world-leading expertise in C. elegans research, combined with our WormGazer™ Technology ensures all aspects of our assays are conducted with the utmost consistency. Our automated approach is optimal for standardised data acquisition with a non-invasive approach. For example, there are no abrupt changes in lighting or temperature, or mechanical disruption to our worm cultures.
Unlike competitors, our technology enables us to maintain worms in a more natural, free-moving environment (as opposed to microchips), to encourage native behaviour and reliable data outcomes. In addition, WormGazer™ Technology allows continuous data acquisition with multiple culture plates per test conditions. Tracking images are taken every 0.8 sec for 160 secs, every 5 mins 24 hrs a day with an extensive duration (up to 14 days). As a result, we can generate a petabyte of relevant data per week. This allows us to reliably detect small changes between test conditions to provide information about whether your product has a tight efficacy window and understand the complexity of dose responses. This rich data is customisable for a multi-faceted healthspan approach, enabling you to select diverse and highly relevant end-points for your research — not just single data-point outcomes.
In addition to Healthspan assays, WormGazer™ technology has diverse outputs available:
- Neuronal functional assays
- Phenotypic disease studies
- Toxicity studies
- Behavioural studies
- Assessing mobility and muscle health
- Chemotaxis
- Exploratory assays
- Lifespan assays
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Registered in England and Wales under Company Number 11579884. All rights reserved.


