Microbiome

Advantages and expertise for microbiotics research

Gut microbiome: A significant target for therapeutics

Research in the last two decades has demonstrated the critical influence that the microbes in our gut have on our overall health. A perturbed gut microbiome is implicated in diverse disease states, and is a significant target for therapeutic intervention

An intrinsic advantage with expert support

C. elegans is an established research model for studying the gut microbiome. Many factors including gut anatomy, human gene homology, a short life cycle and large population number make C. elegans a suitable model for testing the health effects of prebiotics, probiotics and postbiotics.

C. elegans have an intrinsic host-microbe interaction that can be used specifically for microbiome research. Worms feed naturally on bacteria, which can be exploited to study the effects of single microbe strains isolated from the human gut microbiome, bacterial extracts or conditioned media. Combined with our automated WormGazerTM technology, and rich output of data, this confers several benefits for your project.

We elevate the intrinsic advantage of C. elegans for microbiome research with our expert knowledge and rich data output

Our advantage for microbiome studies:

  1. Rapidly test the acute and chronic effects of bacterial strains on multiple functional end-points relevant to human health and quality of life
  2. Ability to distinguish the impact of your product in early-life, mid and late-adulthood 
  3. Rich customisable data with population-scale screening of products that target the gut microbiome 
  4. Consultancy from leading multidisciplinary experts for study design input
  5. Automated WormgazerTM technology with high throughput and data reproducibility
  6. A diverse range of functional assays that allow you to quickly understand the health benefits of your strains and differentiate them from your competitors
  7. Target identification and transgenic approaches to understand mechanisms of action

"We have formed an incredible partnership, which not only has provided AB Biotek with novel information on our formulations, but also Magnitude Biosciences with new technology to implement in their future services. All of this will be reflected in the publications of several papers and the filing of several patents. We hope to maintain this collaboration in future projects and keep developing new formulations to help human health."

Gerald Dard, Managing Director , AB Biotek HNH


"Magnitude Biosciences has proven itself to be a world-leading C. elegans CRO. The team behind the project has been extremely flexible throughout every step of our collaboration, and has been extremely supportive and innovative when it comes to developing new technology to meet our needs. We are not C. elegans experts, but Magnitude Biosciences aided us in fully comprehending the data generated in our studies and ensuring that it was understandable for our particular needs."

María Tintoré, senior scientist at AB Biotek HNH

Get in touch today to find out how we can 
support you to accelerate your research

Privacy Policy
This field is for validation purposes and should be left unchanged.

SERVICES

Contract lab services for your research area

Our customised C. elegans studies help industry leaders generate high-quality, 
reproducible data to answer their research questions in these areas.

Microbiome

A powerful whole
organism model for
microbiome research

Neurodegeneration

A proven whole organism model for neurodegenerative disease
research

Toxicity

A powerful whole organism model for detecting toxicity for the environment and human health

Ageing

A powerful whole
organism model for accelerating ageing research

Transgenics

We can generate C. elegans strains tailored to the exact needs of your project.

Slide
Ageing

A powerful whole
organism model for accelerating ageing research

Slide
Microbiome

A powerful whole organism model for
microbiome research

Slide
Neurodegeneration

A proven whole organism model for neurodegenerative disease
research

Slide
Toxicity

A powerful whole organism model for detecting toxicity for the environment and human health

Slide
Transgenics

We can generate C. elegans strains tailored to the exact needs of your project.

previous arrow
previous arrow
next arrow
next arrow

CONTACT US

Get in touch today to find out how we can support you
to accelerate your research