Pharmaceutical

Fast track your best drug discovery candidates with confidence

Use our transformative approach for high quality in vivo data early on, to de-risk your pipeline

Our expert CRO services provide our pharmaceutical partners with high-quality, robust in vivo data to help prioritise and progress their best clinical candidates within weeks. We combine the advantages of C. elegans as a model organism, with our world-leading expertise for validated, regulation-free testing with human translatability.

Unique technology and expertise

Our fast, economical approach helps augment in vitro studies, and provides predictive in vivo data to de-risk your project — reducing the need for mammalian testing. Our interdisciplinary team bring 80+ years joint C. elegans experience, and we work together to bring you the optimal assays for pharmaceutical applications.

Our patented whole-organism screening platform, VivoScan^™, allows us to screen drug libraries from $1 per compound*, with readouts in a matter of weeks. Our unique bio-photonics platform technology — WormGazer^™, differentiates us significantly from competitors. WormGazer™ generates scalable, multi-end point data for a comprehensive efficacy and safety profile.

We work efficiently to meet diverse data requirements for efficacy, early toxicology, phenotypic and functional endpoints, drug combinations, mechanism of action, target validation and identification. Our transgenics strains can be tailored to your project needs, including custom disease and humanised models.

*per compound pricing dependent on scale

Scalable, in vivo data to prioritise clinical candidates:

A validated, 3R compliant in vivo model for acute and chronic drug testing

Scalable data in weeks, with unique automated WormGazer™ technology

Target identification and transgenic approaches to understand mechanisms of action

De-risk and reduce rodent testing and regulation

Radically reduce timelines and costs, moving from in vitro to in vivo studies

Bespoke CRO assay development and proof of concept studies

Expert interdisciplinary team with 80+ years joint experience as partners

Well-structured, robust data for all in-house formats, publication, patents and investors

“We are excited to be working with Magnitude Biosciences. Their unique approach to generating in vivo data for studying disease models will help us get fast and reliable answers to our research questions.”

Dr. Kjartan Herrik

Principal Scientist,
Lundbeck Pharma

Case Study: Identifying a Lead Candidate for Slowing Ageing with GeroState Alpha

GeroState Alpha is a pharmaceutical company, based at the Buck Institute for Research on Ageing in Novato, California, USA. Magnitude Biosciences worked with Gerostate Alpha to help the pharmaceutical company prioritise their small molecule candidate pipeline for their effects to delay ageing.