Results take at least months with mice or trying to test everything across every cell type in-vitro or using organoids. With worms, you can get the results you need in as little as 3 weeks and still see the effects on whole organisms, not just at a cellular level.
Mice studies typically cost tens of thousands of dollars even for very small studies, and bigger studies can cost hundreds of thousands. Worms show multiple endpoints and can answer some of the same research questions as mice in many areas at a fraction of the cost.
C. elegans have no regulatory or ethical constraints and are 3R compliant.
Results take at least months with mice or trying to test everything across every cell type in-vitro or using organoids. With worms, you can get the results you need in as little as 3 weeks and still see the effects on whole organisms, not just at a cellular level.
Mice studies typically cost tens of thousands of dollars even for very small studies, and bigger studies can cost hundreds of thousands. Worms show multiple endpoints and can answer some of the same research questions as mice in many areas at a fraction of the cost.
C. elegans have no regulatory or ethical constraints and are 3R compliant
C. elegans have many advantages as an in-vivo model but have historically not been easily accessible to industrial R&D because accessing the technologies and specialist knowledge and skill required isn’t easy. In addition, traditional uses of C. elegans are limited by a manual approach to assays. At Magnitude Biosciences, we have two missions: embrace automation to ensure C. elegans studies are reproducible and robust, and bring the benefits of using C. elegans to the biotech, pharma and other industries through our commercial lab services and world-class team of C. elegans and automated imaging experts.
Biotech
Biotech professionals must progress their drug discovery R&D timelines fast in order to make the best use of their funding and IP.
We help you take the jump from petri dish to mammal in-vivo models with confidence and more quickly than going straight to rodent models.
Health and Manufacturing
Consumer goods, manufacturing and other industries investing in R&D want to put the best quality, eco-friendly products out on the market. However, testing your compounds for impact on environmental and human health can lead to overly complex, ethically challenging and time-consuming studies with animal models. C. elegans offers an ethical approach that can get the data you need on your compound in as little as three weeks.
Pharma
The pressure on drug developers is greater than ever and pharma need to look to innovative new tools to stay ahead of the competition. C. elegans offer an NC3Rs-approved avenue to fast-track preclinical research, to save you from or reduce your reliance on high-investment rodent studies.
Academia
You want to progress your research and improve lab operations but access to the right technologies, technological expertise and the time to juggle everything is challenging. We offer high-quality C. elegans lab services, transgenics services, and machine leasing of our unique automated technology to help you stay top of your field.
A powerful whole organism model for microbiome research
A proven whole organism model for neurodegenerative disease research
A powerful whole organism model for detecting toxicity for the environment and human health
A powerful whole organism model for accelerating ageing research
Making transgenics requires specialist equipment, expertise and time.