C.elegans
C. elegans assays add value beyond in vitro and mammal testing for drug development and research.
Microbiome
A fast and reliable method of animal testing for chronic effects of a large number of microbial candidates.
Ageing
Our approach generates reproducible data on the impact your compounds have on quality of life and the slowing of ageing.
Neurodegeneration
Use a proven animal model to test compounds that could slow the degeneration of neurons
Biotech/Pharma
Use C. elegans to demonstrate efficacy and safety and to validate targets.
with our C. elegans expertise and services
with our C. elegans expertise and services
C. elegans assays adds value beyond in-vitro and mammal testing for drug development and research
with our C. elegans expertise and services
A fast and reliable method of animal testing for chronic effects of a large number of microbial candidates.
with our C. elegans expertise and services
C. elegans assays adds value beyond in-vitro and mammal testing for drug development and research
with our C. elegans expertise and services
Use a proven animal model to test compounds that could slow the degeneration of neuron
with our C. elegans expertise and services
Use C. elegans to demonstrate efficacy and safety and to validate targets.
A powerful whole organism model for detecting toxicity for the environment and human health
A powerful whole organism model for detecting toxicity for the environment and human health
A powerful whole organism model for detecting toxicity for the environment and human health
Our customised C. elegans studies help industry leaders generate high-quality,
reproducible data to answer their research questions in these areas.
A powerful whole organism model for microbiome research
A proven whole organism model for neurodegenerative disease research
A powerful whole organism model for detecting toxicity for the environment and human health
A powerful whole organism model for accelerating ageing research
We can generate C. elegans strains tailored to the exact needs of your project.
Biotech
Biotech professionals must progress their drug discovery R&D timelines fast in
order to make the best use of their funding and IP. We help you take the jump from
petri dish to mammal in vivo models with confidence and more quickly than going straight
to rodent models.
Health and Manufacturing
Consumer goods, manufacturing and other industries investing in R&D want to put
the best quality, eco-friendly products out on the market. However, testing your
compounds for impact on environmental and human health can lead to overly complex,
ethically challenging and time-consuming studies with animal models. C. elegans offer
an ethical approach that can get the data you need on your compound in as little as three weeks.
Pharma
The pressure on drug developers is greater than ever and pharma need to look to
innovative new tools to stay ahead of the competition. C. elegans offer an NC3Rs-approved
avenue to fast-track preclinical research, to save you from or reduce your reliance on
high-investment rodent studies.
Academia
You want to progress your research and improve lab operations but access to the
right technologies, technological expertise and the time to juggle everything is
challenging. We offer high-quality C. elegans lab services, transgenics services,
and machine leasing of our unique automated technology to help you stay top of your field.
Take the jump from petri dish to in vivo models with confidence.
Helping industrial R&D get the data they need on their compounds in as little as three weeks.
Fast-track your preclinical research and de-risk high-investment rodent studies.
High-quality C. elegans lab services and machine leasing of our unique automated technology to help you stay top of your field.
Helping industrial R&D get the data they need on their compounds in as little as three weeks.
Fast-track your preclinical research and de-risk high-investment rodent studies.
High-quality C. elegans lab services and machine leasing of our unique automated technology to help you stay top of your field.
You want to progress your research and improve lab operations but access to the right technologies, technological expertise and the time to juggle everything is challenging. We offer high-quality C. elegans lab services, transgenics services, and machine leasing of our unique automated technology to help you access the resources you need to stay top of your field.
You want to progress your research and improve lab operations but access to the right technologies, technological expertise and the time to juggle everything is challenging. We offer high-quality C. elegans lab services, transgenics services, and machine leasing of our unique automated technology to help you access the resources you need to stay top of your field.
You want to progress your research and improve lab operations but access to the right technologies, technological expertise and the time to juggle everything is challenging. We offer high-quality C. elegans lab services, transgenics services, and machine leasing of our unique automated technology to help you access the resources you need to stay top of your field.
You want to progress your research and improve lab operations but access to the right technologies, technological expertise and the time to juggle everything is challenging. We offer high-quality C. elegans lab services, transgenics services, and machine leasing of our unique automated technology to help you access the resources you need to stay top of your field.
Design your experiments in consultation
with our expert team to answer your
research question
We test your compounds for compatibility
with our drug delivery system
We test your compounds for acute and developmental reproductive toxicity
We monitor worm mobility to reveal efficacy and
chronic toxicity of your compound
We evaluate the data to ensure it answers your
research question and deliver a clear, data-rich
report you can present with confidence
We test your compounds for acute and
developmental reproductive toxicity
Design your experiments in consultation
with our expert team to answer your
research question
We test your compounds for compatibility with our drug delivery system
We test your compounds for acute and
developmental reproductive toxicity
We monitor worm mobility to reveal efficacy and chronic toxicity of your compound
We evaluate the data to ensure it answers your research question and deliver a clear, data-rich report you can present with confidence
Design your experiments in consultation
with our expert team to answer your
research question
We test your compounds for compatibilit with our drug delivery system
We test your compounds for acute and
developmental reproductive toxicity
We monitor worm mobility to reveal efficacy and chronic toxicity of your compound
We evaluate the data to ensure it answers your research question and deliver a clear, data-rich report you can present with confidence
Pleased with the professional, efficient level of service we received from Magnitude Biosciences. We were happy to see reproducible and consistent data that has real potential for future screening projects.
Magnitude were very collaborative, efficient and flexible as the experiments progressed. We were impressed with the power of the automated imaging technology and the speed at which we obtained the results which helped us to efficiently prioritise key compounds.
The team at Magnitude Biosciences revealed the power of the C. elegans system in the early stages of drug development. They made us aware of the possibility and merit of using a variety of transgenics techniques in C. elegans to test the positive effects of peptides in models of neurodegeneration. We hope there will be future opportunities to partner with Magnitude Biosciences to help us develop the next generation of therapies.
"Pleased with the professional, efficient level of service we received from Magnitude Biosciences. We were happy to see reproducible and consistent data that has real potential for future screening projects."
Dr Jennifer Tullet
Senior Lecturer, University of Kent.
"Magnitude were very collaborative, efficient and flexible as the experiments progressed. We were impressed with the power of the automated imaging technology and the speed at which we obtained the results which helped us to efficiently prioritise key compounds.''
Dr Peter Hamley
CSO, Samsara Therapeutics - Samsara is a company discovering new medicines for healthy ageing
''The team at Magnitude Biosciences revealed the power of the C. elegans system in the early stages of drug development. They made us aware of the possibility and merit of using a variety of transgenics techniques in C. elegans to test the positive effects of peptides in models of neurodegeneration. We hope there will be future opportunities to partner with Magnitude Biosciences to help us develop the next generation of therapies.''
Dr Penny Hayward
Principal Scientist, PhoreMost Ltd. PhoreMost has developed the protein interference SITESEEKER® platform to drug the undruggable in oncology and ageing.
Take a look at our fat staining assay for ageing research which determines whether caloric restriction could be involved in your test compound's mode of action. Please fill in the form below to download our new Fat Staining Assay Data Sheet:
Hannah Raddings (right) and Alana Mullins (centre) with Magnitude Biosciences Head of Experiments Michael Fasseas (left) Durham, UK - July 29, 2021 Magnitude Biosciences, the world’s leading commercial lab services provider in using the nematode worm C. elegans to accelerate drug discovery and other research in the areas of the gut microbiome, ageing, and neurodegeneration, […]
Originally published in Health Tech World: https://www.htworld.co.uk/interviews/could-c-elegans-be-the-key-to-slowing-ageing/ Health Tech World spoke to Magnitude Biosciences about its groundbreaking work with C. elegans and how it is assisting biotechs in the development of drugs that can slow ageing and tackle age-related neurodegenerative diseases. C. elegans is a tiny worm about a millimetre in length. It’s been used in research since […]
How do we slow the process of Ageing? David Weinkove discusses learnings from the Clubhouse event "The Future of Longevity II"
Magnitude Bioscience CEO, David Weinkove, discusses the application of C. elegans to accelerate the industrial drug discovery process
Take a look at our fat staining assay for ageing research which determines whether caloric restriction could be involved in your test compound's mode of action. Please fill in the form below to download our new Fat Staining Assay Data Sheet:
Hannah Raddings (right) and Alana Mullins (centre) with Magnitude Biosciences Head of Experiments Michael Fasseas (left) Durham, UK - July 29, 2021 Magnitude Biosciences, the world’s leading commercial lab services provider in using the nematode worm C. elegans to accelerate drug discovery and other research in the areas of the gut microbiome, ageing, and neurodegeneration, […]
Originally published in Health Tech World: https://www.htworld.co.uk/interviews/could-c-elegans-be-the-key-to-slowing-ageing/ Health Tech World spoke to Magnitude Biosciences about its groundbreaking work with C. elegans and how it is assisting biotechs in the development of drugs that can slow ageing and tackle age-related neurodegenerative diseases. C. elegans is a tiny worm about a millimetre in length. It’s been used in research since […]
How do we slow the process of Ageing? David Weinkove discusses learnings from the Clubhouse event "The Future of Longevity II"
