The pathway to demonstrate efficacy, safety and to validate targets isn’t always clear, but time is of the essence. Biotech professionals must progress their drug discovery R&D timelines fast in order to make the best use of their funding and IP.
To bring investors and Big Pharma onboard, biotechs need data that is reliable, reproducible and clear. However, there is a high safety/efficacy failure rate of drug candidates from in-vitro research to mouse studies, and testing chronic drug effects on mice is costly in terms of time as well as budget, so options to de-risk going to this stage are limited.
- We derisk your drug progressing from in-vitro to mice. Using our C. elegans technology will tell you what chemical series is best used for your target, what the in-vivo toxicity of your favoured compound(s) are, which of your possible targets will work best in-vivo, and if your chemical series or compounds are effective in-vivo, at a fraction of the cost and time of using mice.
- We accelerate your project by doing acute and chronic drug effect testing faster and cheaper than mouse models. C. elegans automated Healthspan whole-life experiments last weeks, not months. We stick to our lab schedules, respond quickly to your queries, and ensure your study is set up quickly.
- We increase your chance of success by generating high quality, consistent, well-structured data in a detailed report that is publishable and easily understood, by your science team, your investors and your market segment . Our scientists will help you decide which analyses are most relevant for your endpoint and get the most of your data.
- Your project matters - we offer a solution customised to your needs, regardless of your location, and we ensure your IP is well-protected at every stage. We develop assays where C. elegans is truly relevant and valuable to answering your research questions, and never recommend C. elegans where a better solution exists.
- We partner with you as an expert expansion on your team. Our team is the best in the business. We offer standardised experiments in worms picked by experts, for high consistency and robustness of testing conditions.
- We help you take the leap from petri dish to mammal in-vivo models with confidence. Our C. elegans technology shows how your drug works in a whole organism before going to mice.
We are always happy to design novel custom assays to fit your needs, so don't hesitate to ask.