VivoScan™
in vivo High-Throughput Screening
Scaling up drug discovery by orders of magnitude
Progressing from candidate to clinic is no easy feat. Out of every 10,000 compounds screened, only 1 reaches the market1.
We believe in the power of the worm to address the unmet needs of pharmaceutical R&D but didn’t have the scale the industry needed. Our founders were challenged by key players in drug discovery to dramatically increase the throughput of in vivo compound screening while decreasing cost. After 2 years of pioneering innovation, we launched VivoScan™: the world’s first whole-organism phenotypic screening platform at high-throughput scale.
Live C. elegans are liquid-cultured and precision-dispensed into 384-well plates. Survival and mobility are continuously monitored with rapid widefield video imaging, enabling in vivo screening of age-related and disease phenotypes without the regulatory constraints of mammalian models. Our patented technology allows us to screen drug libraries from $1 per compound*, with readouts in a matter of weeks.
*per compound pricing dependent on scale
Download our data insight pack and discover how VivoScan™ simultaneously detects healthspan, lifespan, and caloric restriction at high-throughput scale
Back to the Beginning
VivoScan™ is not a replacement for cell-based screening, but an expansion to your data package for more informed decision making.
Most early discovery pipelines are built on low-dimensional inputs. Cell-based HTS, single biomarkers, and simplified in vitro models generate fast data, but they strip out system-level interactions. These limitations propagate downstream, constraining in silico models, misdirecting lead optimisation, and contributing to late-stage failure.
By supplementing existing HTS, in silico, and medicinal chemistry workflows with scalable in vivo data, VivoScan™ helps eliminate false positives and negatives, de-risking preclinical and clinical studies before they begin.
VivoScan™ by the numbers:
Estimate the cost of your project:
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