C. elegans as a toxicity testing model

C. elegans is a well-characterised, ethical model for toxicity testing with diverse applications in drug development, compound and environmental fields, with human translatability.

Our toxicity assays and testing advantage

C. elegans, combined with our WormGazer™ technology and CRO expertise, offers many benefits over rodent models, including reduced timeframes and costs, no regulatory requirements, and significantly streamlined study designs. Our approach enables you to eliminate unsuccessful candidates at an early stage of your product development pipeline.

Our advantage for toxicity testing

• Reduced timeframes, costs and regulatory requirements
• An ethical alternative model for toxicity testing compared to more sentient mammals 
• Standardised, population-scale acute and chronic testing for mutation and compound effects on healthspan 
• Rapid, sensitive and scalable data-acquisition in DART assays with WormGazer™ technology and progeny number 
• Streamlined study designs with multidisciplinary expert input
• Invaluable prescreen to eliminate compounds for toxicity and prioritise product pipeline
•  An established track record of relevance to many human diseases like neurodegeneration, cancer, and metabolism

Transferable data

C. elegans serve as a versatile model for studying diseases due to its conserved genetic pathway. This makes C. elegans a biologically relevant and efficient model for toxicity studies, providing valuable insights into the potential effects of chemicals on human health and development.